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HPLC and UPLC Analysis

High-performance liquid chromatography (HPLC) and ultra-high-performance liquid chromatography (UPLC) are the foundation of our analytical services. We run reverse-phase, HILIC, size-exclusion, and hydrophobic interaction chromatography with UV/PDA and refractive index detection.

What we measure

Small molecules, natural products, pharmaceuticals, metabolites, sugars, organic acids, proteins (by SEC/HIC), food additives, and more. If it dissolves and can be separated on a column, we can probably measure it.

Refractive index detection

Available on our Shimadzu instruments. Essential for compounds that UV cannot detect: sugars, polyols, organic acids, ethanol. Many competitors do not offer RID. If you are doing fermentation work and need to track glucose consumption or organic acid production alongside your target compound, this matters.

How it works

  1. You tell us what you need to measure and what your samples are.
  2. We configure the method during Method Setup (from £800).
  3. You send samples. We run them and return results.
  4. For future batches, select your method and check out. No repeat setup needed.

See our pricing page for detailed cost examples.

Get in touch to discuss your measurement

Get in touch